Product Info Summary
SKU: | A02502Y516 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | ELISA, Flow Cytometry, IHC, WB |
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Product info
Product Name
Anti-Phospho-Trk C (Y516) NTRK3 Antibody
SKU/Catalog Number
A02502Y516
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Phospho-Trk C (Y516) NTRK3 Antibody catalog # A02502Y516. Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Phospho-Trk C (Y516) NTRK3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02502Y516)
Host
Rabbit
Contents
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human Trk C around the phosphorylation site of Y516.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02502Y516 is reactive to NTRK3 in Human, Mouse, Rat
Applications
A02502Y516 is guaranteed for ELISA, Flow Cytometry, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
94.428kDa
Background of TrkC
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A.
Ladias J.A.A., Science 251:561-565(1991).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Wang L.H., Gene Expr. 1:207-216(1991).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
Validation Images & Assay Conditions
Click image to see more details
Figure 2. Immunohistochemistry validation of NTRK3 using Anti-Phospho-Trk C (Y516) NTRK3 Antibody (A02502Y516).
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°CClick image to see more details
Figure 1. Western blotting validation for Anti-Phospho-Trk C (Y516) NTRK3 Antibody A02502Y516
Western Blot (WB) analysis of HeLa cells using Phospho-Trk C (Y516) polyclonal antibody.Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For NTRK3 (Source: Uniprot.org, NCBI)
Gene Name
NTRK3
Full Name
NT-3 growth factor receptor
Weight
94.428kDa
Superfamily
protein kinase superfamily
Alternative Names
EC 2.7.10; EC 2.7.10.1; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; ETV6-NTRK3 fusion; gp145(trkC); GP145-TrkC; Neurotrophic tyrosine kinase receptor type 3; neurotrophic tyrosine kinase, receptor, type 3; NT 3 receptor; NT-3 growth factor receptor; NTRK3; TrkC tyrosine kinase; TrkC; trk-C; TRKCneurotrophin 3 receptor; tyrosine kinase receptor C NTRK3 GP145-TrkC, TRKC, gp145(trkC) neurotrophic receptor tyrosine kinase 3 NT-3 growth factor receptor|ETS related protein-neurotrophic receptor tyrosine kinase fusion protein|ETV6-NTRK3 fusion|neurotrophic tyrosine kinase, receptor, type 3|tyrosine kinase receptor C
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on NTRK3, check out the NTRK3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for NTRK3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Phospho-Trk C (Y516) NTRK3 Antibody (A02502Y516)
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No publications found for A02502Y516
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